• Home
  • Welcome and Orientation
  • About This Guide
  • Patient Transfers
  • AAA
  • Anticoagulation Reversal
  • Aortic Dissection
  • ARDS/Mechanical Vent
  • Atrial Fibrillation
  • Brain Death
  • Crash Cart/Defibrillator
  • CSW/SIADH
  • Cricothyrotomy
  • Cuff Leak. What is it?
  • Delirium/Antipsychotics
  • DKA/Other Ketoacidosis
  • EVD AND ICP MONITORS
  • ETOH Withdrawal
  • Extubation Readiness
  • Febrile Neutropenia
  • Fluids
  • GI Bleeds
  • Group A Streptococcus
  • Hypertension PRNs
  • Lido With Epi Recipe
  • Lines & Tubes on CXR
  • Lumbar Drains
  • Lung Volume Recruitment
  • Massive Transfusion
  • O2 Delivery Devices
  • Pacemaker Insertion
  • Pain/Analgesia
  • Pocket Pressor Recipes
  • Pulmonary Embolism/PERT
  • Respiratory Failure
  • ROSC
  • Sedation in ICU
  • Seizures/Status
  • Shock and Sepsis
  • Subarachnoid Hemorrhage
  • Swan Ganz Catheter Setup
  • TBI/EVD/ICP monitoring
  • TEVAR
  • Toxicology/Overdose
  • Tracheostomies AND THT
  • Trauma Patients in ICU
  • Tumor Lysis Syndrome
  • Vasoactive Medications
  • Ultrasound Guided Lines
  • More
    • Home
    • Welcome and Orientation
    • About This Guide
    • Patient Transfers
    • AAA
    • Anticoagulation Reversal
    • Aortic Dissection
    • ARDS/Mechanical Vent
    • Atrial Fibrillation
    • Brain Death
    • Crash Cart/Defibrillator
    • CSW/SIADH
    • Cricothyrotomy
    • Cuff Leak. What is it?
    • Delirium/Antipsychotics
    • DKA/Other Ketoacidosis
    • EVD AND ICP MONITORS
    • ETOH Withdrawal
    • Extubation Readiness
    • Febrile Neutropenia
    • Fluids
    • GI Bleeds
    • Group A Streptococcus
    • Hypertension PRNs
    • Lido With Epi Recipe
    • Lines & Tubes on CXR
    • Lumbar Drains
    • Lung Volume Recruitment
    • Massive Transfusion
    • O2 Delivery Devices
    • Pacemaker Insertion
    • Pain/Analgesia
    • Pocket Pressor Recipes
    • Pulmonary Embolism/PERT
    • Respiratory Failure
    • ROSC
    • Sedation in ICU
    • Seizures/Status
    • Shock and Sepsis
    • Subarachnoid Hemorrhage
    • Swan Ganz Catheter Setup
    • TBI/EVD/ICP monitoring
    • TEVAR
    • Toxicology/Overdose
    • Tracheostomies AND THT
    • Trauma Patients in ICU
    • Tumor Lysis Syndrome
    • Vasoactive Medications
    • Ultrasound Guided Lines
  • Home
  • Welcome and Orientation
  • About This Guide
  • Patient Transfers
  • AAA
  • Anticoagulation Reversal
  • Aortic Dissection
  • ARDS/Mechanical Vent
  • Atrial Fibrillation
  • Brain Death
  • Crash Cart/Defibrillator
  • CSW/SIADH
  • Cricothyrotomy
  • Cuff Leak. What is it?
  • Delirium/Antipsychotics
  • DKA/Other Ketoacidosis
  • EVD AND ICP MONITORS
  • ETOH Withdrawal
  • Extubation Readiness
  • Febrile Neutropenia
  • Fluids
  • GI Bleeds
  • Group A Streptococcus
  • Hypertension PRNs
  • Lido With Epi Recipe
  • Lines & Tubes on CXR
  • Lumbar Drains
  • Lung Volume Recruitment
  • Massive Transfusion
  • O2 Delivery Devices
  • Pacemaker Insertion
  • Pain/Analgesia
  • Pocket Pressor Recipes
  • Pulmonary Embolism/PERT
  • Respiratory Failure
  • ROSC
  • Sedation in ICU
  • Seizures/Status
  • Shock and Sepsis
  • Subarachnoid Hemorrhage
  • Swan Ganz Catheter Setup
  • TBI/EVD/ICP monitoring
  • TEVAR
  • Toxicology/Overdose
  • Tracheostomies AND THT
  • Trauma Patients in ICU
  • Tumor Lysis Syndrome
  • Vasoactive Medications
  • Ultrasound Guided Lines

Massive Transfusion

Call a Code Bleed

Civic: 14328

General: 78302

2 Large Bore IVs (at least)

2 Blood Warmers and/or the Level 1 Rapid Infuser

Forced Air Blanket on patient (blood won't clot in a hypothermic milieu)

Box 1

Box 1

4 Units PRBC

Box 2

Box 1

4 Units PRBC

4 Units FFP

1 Unit Platelets

Box 3

4 Units PRBC

2 Units FFP

4g Fibrinogen

Tranexamic Acid

1g IV q8h or infusion














Calcium Chloride

Calcium Chloride

1g after every 4 units of blood 

  • blood contains citrate and binds calcium
  • Calcium is an essential cofactor in the coagulation cascade

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ANTICOAGULATION REVERSAL

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